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Rev. Soc. Bras. Clín. Méd ; 16(4): 196-202, out.-dez. 2018. tab., graf.
Article in Portuguese | LILACS | ID: biblio-1025785

ABSTRACT

OBJETIVO: Analisar a reperfusão miocárdica após intervenção coronariana percutânea primária em diabéticos e não diabéticos. MÉTODOS: Estudo caso-controle prospectivo, realizado no período de janeiro de 2013 a março de 2014, incluindo pacientes com diagnóstico de infarto agudo do miocárdio com menos de 12 horas do início dos sintomas e submetidos à terapia de reperfusão com intervenção coronariana percutânea primária. Foi realizada avaliação do blush miocárdico, da resolução do supradesnivelamento de segmento ST >50% em 90 e em 180 minutos e do Thrombolysis in Myocardial Infarction (TIMI) frame count corrigido <40 quadros. RESULTADOS: Foram incluídos 201 pacientes no estudo, sendo 32 diabéticos. Levando em consideração os marcadores de reperfusão miocárdica estudados, indivíduos diabéticos tiveram menor resolução do segmento ST, menor blush miocárdico e maior TIMI frame count após angioplastia primária quando comparados aos não diabéticos. CONCLUSÕES: Diabéticos apresentaram piores índices de reperfusão miocárdica pós-angioplastia primária comparados aos não diabéticos. (AU)


OBJECTIVES: To analyze myocardial reperfusion following primary percutaneous coronary intervention in diabetic and non-diabetic patients. METHODS: This is a prospective casecontrol study, conducted from January 2013 to March 2014, including patients diagnosed with acute myocardial infarction less than 12 hours after the onset of symptoms, and undergoing reperfusion therapy with Primary percutaneous coronary intervention. The myocardial blush, ST-segment elevation >50% resolution in 90 and 180 minutes, and corrected Thrombolysis Myocardial Infarction (TIMI) frame count <40 frames were evaluated. RESULTS: A total of 201 patients were included in the study, of which 32 were diabetic. Taking the studied myocardial reperfusion markers into consideration, diabetic patients had lower ST segment resolution, lower myocardial blush, and higher TIMI frame count after primary angioplasty when compared to non-diabetics. CONCLUSIONS: Diabetic patients presented worse myocardial reperfusion rates after primary angioplasty when compared to non-diabetic patients. (AU)


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Myocardial Reperfusion , Diabetes Complications , Percutaneous Coronary Intervention , Tobacco Use Disorder , Angioplasty , Diabetes Mellitus/surgery , Renal Insufficiency , Dyslipidemias , ST Elevation Myocardial Infarction/surgery , Hypertension
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